Publications from 2001

Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis.
Gulick AM, Schmidt DM, Gerlt JA, Rayment I.
Biochemistry. 2001 Dec 25;40(51):15716-24. Pubmed

Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases.
Schmidt DM, Hubbard BK, Gerlt JA.
Biochemistry. 2001 Dec 25;40(51):15707-15. Pubmed

Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli.
Gulick AM, Hubbard BK, Gerlt JA, Rayment I.
Biochemistry. 2001 Aug 28;40(34):10054-62. Pubmed

The lesser "burden borne" by o-succinylbenzoate synthase: an "easy" reaction involving a carboxylate carbon acid.
Taylor EA, Palmer DR, Gerlt JA.
J Am Chem Soc. 2001 Jun 20;123(24):5824-5. No abstract available. Pubmed

Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies.
Gerlt JA, Babbitt PC.
Annu Rev Biochem. 2001;70:209-46. Review. Pubmed

The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters.
Holden HM, Benning MM, Haller T, Gerlt JA.
Acc Chem Res. 2001 Feb;34(2):145-57. Pubmed

Barrels in pieces?
Gerlt JA, Babbitt PC.
Nat Struct Biol. 2001 Jan;8(1):5-7. No abstract available. Pubmed