Click on the button to start or restart the animation. Make sure the
coordinate data file has loaded, which takes time. The script file may
also take some time to load.
Use the scroll bar to read an explanation, and for access to supplementary
The structures used in this animation are a composite from the sets
of coordinates kindly made available by Dr. Ed Berry, of the bc1-complex
from chicken heart mitochondria, and by Dr. S. Iwata, of the beef heart
mitochondrial complex in P6522 and P65 crystals.
The coordinates from the solved structures were supplemented with models
for the quinone, quinol, and semiquinone substrates needed to show their
involvement in the catalytic cycle. The composite file includes coordinates
for the different components, in different configurations, involved in
turnover of the complex. Click here for a
summary of the files, and their construction.