The initial view is of the three subunits from a "functional" monomer, presented as a stereo pair for "crossed-eye" viewing.
Coordinates from the Zhang et al. native complex from chicken heart mitochondrial
complex have been supplemented by additional coordinates to provide the
working model (see below).
The structures used in this animation are a composite from the sets
of coordinates kindly made available by Dr. Ed Berry, of the bc1-complex
from chicken heart mitochondria, and by Dr. S. Iwata, of the beef heart
mitochondrial complex in P6522 and P65 crystals.
The coordinates from the solved structures were supplemented with models
for the quinone, quinol, and semiquinone substrates needed to show their
involvement in the catalytic cycle. The composite file includes coordinates
for the different components, in different configurations, involved in
turnover of the complex.
A detailed explanation of the model is provided in the original Chime-based version, which has extensive notes.
Click her for an explanation of the model
Click here for a Chime-based exploration of
the complete chicken complex. Click here for a Chime tutorial
on the structure/function interface, based on the three catalytic subunits
of a "functional" monomer
(The above Chime-based links will only work if you download and install the Chime plug-in for Netscape).