Mechanism of Estrogen Receptor Regualtion of Gene Transcription
Krieg, A.J., Krieg, S.A., Ahn, B.S., and Shapiro, D.J. (2004) "Interplay Between Estrogen Response Element Sequence and Ligands Controls in Vivo Binding of Estrogen Receptor to Regulated Genes," J. Biol. Chem. 279, 5025-34. [Abstract]
Wang, S., Ahn, B.S., Harris, R., Nodeen, S.K. and Shapiro, D.J. (2004) "A Fluorescence Anisotropy Microplate Assay for Analysis of Steroid Receptor DNA Interactions," Submitted for publication.
Obrero, M., Yu, D.V., and Shapiro, D.J. (2002) "Estrogen Receptor-dependent and Estrogen Receptor-independent Pathways for Tamoxifen and 4-hydroxytamoxifen-induced Programmed Cell Death," J. Biol. Chem. 277, 45695-703.
Regulation and Function of Proteinase Inhibitor 9 (PI-9)
Kannan-Thulasiraman, P. and Shapiro, D.J. (2002) "Modulators of Inflammation Use Nuclear Factor-kappa B and Activator Protein-1 Sites to Induce the Caspase-1 and Granzyme B Inhibitor, Proteinase Inhibitor 9," J. Biol. Chem. 277, 41230-9.
Estrogen and Vigilin Control of RNA Metabolism
Dodson, R.E., Goolsby, K.M., Acena-Nagel. M., Mao, C. and Shapiro, D.J. (2003) "RNA Gel Shift Assays for Analysis of Hormone Control of mRNA Stability," Methods in Enzymology 364, 350-61. [Abstract]
Goolsby, K.M. and Shapiro, D.J. (2003) "RNAi-mediated Depletion of the 15 KH Domain Protein, Vigilin, Induces Death of Dividing and Non-dividing Human Cells but does not Initially Inhibit Protein Synthesis," Nucleic Acids Res. 31, 5644-53. [Abstract]