Biology 100 and 101
University of
Illinois

Integrative Biology
100 and 101



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Fall 2009

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Scoring Rubric for Take-Home Assignment #6 Fall 2009

Refer to my key on the web following the due date for more information concerning the  drawing for Question #1.

Question #1 Gene expression:(10 Pts)

Has the student correctly used the following terms in the context of illustrating the expression of the dominant (normal) allele for HBB, the beta globin chain of hemoglobin.? (there are 20 terms, each worth half a point).

    nucleus 1/2 point ____
    dominant (normal) allele for HBB, the beta
    globin chain of hemoglobin
    1/2 point ____
    DNA 1/2 point ____
    transcription 1/2 point ____
    RNA Polymerase
    1/2 point ____
    mRNA 1/2 point ____
    mRNA processing + introns and exons 1/2 point ____
    cytoplasm 1/2 point ____
    translation 1/2 point ____
    ribosome 1/2 point ____
    rRN
    1/2 point ____
    codon 1/2 point ____
    tRNA 1/2 point ____
    anticodon 1/2 point ____
    amino acid 1/2 point ____
    protein folding 1/2 point ____
    the beta chain of  the hemoglobin protein 1/2 point ____
    complete hemoglobin molecule 1/2 point ____
    red blood cells 1/2 point ____
    capillaries 1/2 point ____

Question 2. Mutation: (10 Pts)

Has the student correctly included the following components in his/her answers?

Part a.

    .....ACT CCT GAG GAG AAG TCT.....
    .....TGA GGA CTC CTC TTC AGA..... Transcribed strand (template strand)
    .....??? ??? ??? ??? ??? ???..... Messinger RNA 1/2 point
    .....? ? ? ? ? ?..... Amino Acids 1/2 point

Parts b, c, and d


    Part b Part c
    Part d
    1.  the original DNA
    1/2 pt.
    1/2 pt.
    1/2 pt.
    2.  the mutated DNA  
    1/2 pt.
    1/2 pt.
    1/2 pt.
    3.  the new mRNA strand
    1/2 pt.
    1/2 pt.
    1/2 pt.
    4.  the new sequence of amino acids
    1/2 pt.
    1/2 pt.
    1/2 pt.
    5.  naming the type of mutation and
         effect on  amino acids and protein function

    1 pt.
    1 pt.
    1 pt.