Integrative Biology
100 and 101

Scoring Rubric for Take-Home Assignment #5 Fall 2009

Refer to my key on the web following the due date for more information concerning the chromosome drawings.

Question #1 Autosomal Recessive Trait (5 points)

Probability/chance that the couple's first child will be born a carrier of Tay-Sachs disease?	2 points ____
There should be a Punnett square indicating the target genotypes or some logical explanation of the cross to explain how the probability was derived.	3 points ____

Question #2 Autosomal Dominant Trait (5 points)

Is there a chance that the young woman's child has inherited the dominant Huntington disease gene? Yes or No	2 points ____
There should be one or more Punnett squares indicating the target genotypes or some logical explanation of the cross to explain how the probability was derived.	3 points ____

Question #3 Aneuploidy and Nondisjunction (5 points)

Set of diagrams showing how a mistake during meiosis in the development of gametes would result in a gamete with two Y chromosomes.	2 points ____
Diagram or explanation of the production of a child with the XYY chromosome combination.	2 points ____
Would the mother or the father be "responsible" for this aneuploid condition in a child? -- Explain your choice.	1 point ____

Question #4 Two Gene Genetics and X-linkage (5 points)

Correct probability (chance) that the couple will have a girl who has the fish odor syndrome AND SCID.	2 points ____
There should be one or two Punnett squares indicating the target genotypes or some logical explanation of the cross to explain how the probability was derived. This could also be a multiplication of fish odor probabilities and SCID probabilities.	3 points ____