Integrative Biology 101
Lab Class, October 12-13
Web Resources for
Cell Reproduction: Mitosis and Meiosis

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Related Assignments:

Take-Home Assignment #4 Meiosis and Genetics Due At Lecture Monday October 21

Take-Home Assignment #5 Human Genetics At Lecture Monday October 26

Second Moodle Assignment Due by 8:00 AM, Monday October 28

Web Resources for Cell Reproduction: Mitosis and Meiosis Lab

Lecture 9: Cell Reproduction, Chromosomes, and DNA

Lecture 10: Organism Reproduction: Meiosis and Fertilization

Lecture 11: Heredity and Meiosis

DNA and Cromosome structure

• Chromosomes are made of DNA (Hoefnagels pg 157, figure 8.2

• DNA Wrapping and DNA Replication Movie

• DNA Structure
  

• Nucleotides and Complementary Base Pairing - A-T & C-G (Hoefnagels Page 142, fig. 7.8)

• DNA replication Hoefnagels, pg 144, figure 7.11

• Single or Replicated Chromosomes? Hoefnagels Page 157, figure 8.3

• Human Chromosomes Hoefnagels Page 158, figure 84.5

• Interactive Chromosome/Gene Poster from Gene Gateway - Exploring Genes and Genetic Disorders

The Cell Cycle

• Cell Cycle Diagram Hoefnagels Page 160, fig. 8.5

• Visit cellsalive.com and select Cell Cycle

• The Cell Cycle from geneticsolutions.com

Note the form of the chromosomes (duplicated or not) at each phase of the cell cycle.

Mitosis

• Mitosis - first half hoefnagels Pg. 162, fig. 8.7

• Mitosis - the middle (metaphase) hoefnagels Pg. 161, fig. 8.6

• Mitosis - Second half hoefnagels Pg. 163, fig. 8.7

• Mitosis Animation (narrated)

• Synchronized Swimming Mitosis (music

• Mitosis in relation to the cell cycle from geneticsolutions.com

Note the form of the chromosomes (replicated or not) at the beginning, during, and at the end of mitosis.

• Single or Replicated Chromosomes? Hoefnagels Page 157, figure 8.3

Meiosis, Sexual Reproduction and Heredity

• The General Sexual Life Cycle

• Review of Chromosomes

• Homologous chromosomes Hoefnagels. Page 196, fig. 10.1

• Single or Replicated Chromosomes? Hoefnagels Page 157, figure 8.3

• Overview of Meiosis Hoefnagels pg. 179, fig. 9.5

• Details of Meiosis Hoefnagels pg. 180-1, fig. 9.6

• Meiosis I Hoefnagels pg. 180, fIg. 9.6.1

• Meiosis II Hoefnagels pg. 180, fIg. 9.6.2

• Meiosis and the Formation of Gametes

• Meiosis and the Development of sperm Hoefnagels pg. 188, fig. 9.15

• Meiosis and the Development of eggs Hoefnagels pg. 189, fig. 9.16

• Timing of Development of sperm and eggs Lewis, et. al. pg. 180, fig. 10.17

• Genetic Recombinations during Meiosis

• Independent Assortment of Homologoius Chromosomes
  

  • Possible arrangements of homologous Chromosomes during meiosis Hoefnagels pg. 183, figure 9.8

  • Independent assortment Hoefnagels pg. 203, figure 10.9

  • Independent Assortment of Alleles from Sumanasinc.com

• Crossing Over of Non-Sister Chromatids of Homologous Chromosomes
  

• Crossing Over Hoefnagels, pg. 182, fig. 9.7

• Meiosis with Crossing Over from Sumanasinc.com

• Gamete variation by Crossing Over depends on the relative location of linked gene loci.

• Fertilization and Predicting Heredity (Genetics)

• Solving Genetics Problems

• Punnett Square diagram of a cross involving only ONE GENE (Monohybrid) - Select "Animation" from the choices at the bottom of the screen. (from DNA from the Beginning)

• Autosomal Recessive and Dominant inheritence compared

• Punnet square analysis of a cross involving TWO GENES. (Dihybrid) - Select "Problem" from the choices at the bottom of the screen. (from DNA from the Beginning)

• Aneuploidy - Extra or missing chromosomes resulting from nondisjunction.

• Nondisjunction is the failure of a homologous chromosme pair to separate (become disjunct) during meiosis results in aneuploidy.

• Nondisjunction can occur in either meiosis I
  

• or meiosis II . (Hoefnagels, pg. 185, fig. 9.11)