Bian, Q. and A.S. Belmont, Revisiting higher-order and large-scale chromatin organization, Curr Opin Cell Biol. 2012 March 27 [Epub ahead of print]

Belmont AS, Hu Y, Sinclair PB, Wu W, Bian Q, I. Kireev, Insights into interphase large-scale chromatin structure from analysis of engineered chromosome regions.

Cold Spring Harb Symp Quant Biol. 2011 Apr 5. [Epub ahead of print] PMID: 21467143

Masui, O., Bonnet, I., Le Baccon, P., Brito, I., Pollex, T., Murphy, N., Hupe, F., Barillot, E., Belmont, A.S., E. Heard, Live-cell chromosome dynamics and outcome of X chromosome pairing events during ES cell differentiation. Cell 145:447-458 (2011)

Belmont, A.S., Estrogen fueled, nuclear kiss: did it move for you?, Nucleus 1: 440-443 (2010) PMID: 21326827

Hu, Y., Plutz, M., A. S. Belmont, Hsp70 gene-nuclear speckle association is Hsp70 promoter specific, JCB 191:711-719 (2010) PMCID: PMC2983068

Sinclair, P., Bian, Q., Plutz, M., Heard, E., A.S. Belmont, Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions, JCB 190: 761-776 (2010) PMCID: PMC2935575 (subject of a JCB biobytes Podcast: http://jcb.rupress.org/content/190/5/761/suppl/DC2)

Bian Q, Belmont AS. BAC TG-EMBED: one-step method for high-level, copy-number dependent, position-independent transgene expression. Nucleic Acids Res. 2010 Jun 1; 38 (11) :e127. PubMed PMID:20385594; PubMed Central PMCID: PMC2887973.

Balamotis MA, Pennella MA, Stevens JL, Wasylyk B, Belmont AS, Berk AJ. Complexity in transcription control at the activation domain-mediator interface. Sci Signal. 2009 May 5; 2 (69) :ra20. PubMed PMID:19417216; PubMed Central PMCID: PMC2774526.

Hu Y, Kireev I, Plutz M, Ashourian N, Belmont AS. Large-scale chromatin structure of inducible genes: transcription on a condensed, linear template. J Cell Biol. 2009 Apr 6; 185 (1) :87-100. PubMed PMID:19349581; PubMed Central PMCID: PMC2700507.

Strukov YG, Belmont AS. Mitotic chromosome structure: reproducibility of folding and symmetry between sister chromatids. Biophys J. 2009 Feb 18; 96 (4) :1617-28. PubMed PMID:19217877; PubMed Central PMCID: PMC2717231.

Kireev I, Lakonishok M, Liu W, Joshi VN, Powell R, Belmont AS. In vivo immunogold labeling confirms large-scale chromatin folding motifs. Nat Methods. 2008 Apr; 5 (4) :311-3. PubMed PMID:18345005.

Rego A, Sinclair PB, Tao W, Kireev I, Belmont AS. The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure. J Cell Sci. 2008 Apr 1; 121 (Pt 7) :1119-27. PubMed PMID:18334550.

Deng H, Bao X, Cai W, Blacketer MJ, Belmont AS, Girton J, Johansen J, Johansen KM. Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila. Development. 2008 Feb; 135 (4) :699-705. PubMed PMID:18199578.

Chuang CH, Belmont AS. Moving chromatin within the interphase nucleus-controlled transitions?. Semin Cell Dev Biol. 2007 Oct; 18 (5) :698-706. PubMed PMID:17905613; PubMed Central PMCID: PMC2117624.

Novikov DV, Kireev I, Belmont AS. High-pressure treatment of polytene chromosomes improves structural resolution. Nat Methods. 2007 Jun; 4 (6) :483-5. PubMed PMID:17486085.

Belmont AS. Mitotic chromosome structure and condensation. Curr Opin Cell Biol. 2006 Dec; 18 (6) :632-8. PubMed PMID:17046228.

Chuang CH, Carpenter AE, Fuchsova B, Johnson T, de Lanerolle P, Belmont AS. Long-range directional movement of an interphase chromosome site. Curr Biol. 2006 Apr 18; 16 (8) :825-31. PubMed PMID:16631592.

Brink MC, van der Velden Y, de Leeuw W, Mateos-Langerak J, Belmont AS, van Driel R, Verschure PJ. Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting. Histochem Cell Biol. 2006 Jan; 125 (1-2) :53-61. PubMed PMID:16283356.

Levi V, Ruan Q, Plutz M, Belmont AS, Gratton E. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys J. 2005 Dec; 89 (6) :4275-85. PubMed PMID:16150965; PubMed Central PMCID: PMC1366992.

Verschure PJ, van der Kraan I, de Leeuw W, van der Vlag J, Carpenter AE, Belmont AS, van Driel R. In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol Cell Biol. 2005 Jun; 25 (11) :4552-64. PubMed PMID:15899859; PubMed Central PMCID: PMC1140641.

Carpenter AE, Memedula S, Plutz MJ, Belmont AS. Common effects of acidic activators on large-scale chromatin structure and transcription. Mol Cell Biol. 2005 Feb; 25 (3) :958-68. PubMed PMID:15657424; PubMed Central PMCID: PMC544008.

Chuang CH, Belmont AS. Close encounters between active genes in the nucleus. Genome Biol. 2005; 6 (11) :237. PubMed PMID:16277755; PubMed Central PMCID: PMC1297641.

Chen D, Belmont AS, Huang S. Upstream binding factor association induces large-scale chromatin decondensation. Proc Natl Acad Sci U S A. 2004 Oct 19; 101 (42) :15106-11. PubMed PMID:15477594; PubMed Central PMCID: PMC524054.

Kireeva N, Lakonishok M, Kireev I, Hirano T, Belmont AS. Visualization of early chromosome condensation: a hierarchical folding, axial glue model of chromosome structure. J Cell Biol. 2004 Sep 13; 166 (6) :775-85. PubMed PMID:15353545; PubMed Central PMCID: PMC2172117.

Dietzel S, Zolghadr K, Hepperger C, Belmont AS. Differential large-scale chromatin compaction and intranuclear positioning of transcribed versus non-transcribed transgene arrays containing beta-globin regulatory sequences. J Cell Sci. 2004 Sep 1; 117 (Pt 19) :4603-14. PubMed PMID:15331668.

Carpenter AE, Ashouri A, Belmont AS. Automated microscopy identifies estrogen receptor subdomains with large-scale chromatin structure unfolding activity. Cytometry A. 2004 Apr; 58 (2) :157-66. PubMed PMID:15057969.

Carpenter AE, Belmont AS. Direct visualization of transcription factor-induced chromatin remodeling and cofactor recruitment in vivo. Methods Enzymol. 2004; 375:366-81. PubMed PMID:14870678.

Strukov YG, Wang Y, Belmont AS. Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes. J Cell Biol. 2003 Jul 7; 162 (1) :23-35. PubMed PMID:12835314; PubMed Central PMCID: PMC2172725.

Belmont A. Dynamics of chromatin, proteins, and bodies within the cell nucleus. Curr Opin Cell Biol. 2003 Jun; 15 (3) :304-10. PubMed PMID:12787772.

Li Y, Danzer JR, Alvarez P, Belmont AS, Wallrath LL. Effects of tethering HP1 to euchromatic regions of the Drosophila genome. Development. 2003 May; 130 (9) :1817-24. PubMed PMID:12642487.

Memedula S, Belmont AS. Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16. Curr Biol. 2003 Feb 4; 13 (3) :241-6. PubMed PMID:12573221.

Belmont AS. Mitotic chromosome scaffold structure: new approaches to an old controversy. Proc Natl Acad Sci U S A. 2002 Dec 10; 99 (25) :15855-7. PubMed PMID:12461163; PubMed Central PMCID: PMC138527.

Vazquez J, Belmont AS, Sedat JW. The dynamics of homologous chromosome pairing during male Drosophila meiosis. Curr Biol. 2002 Sep 3; 12 (17) :1473-83. PubMed PMID:12225662.

Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS. Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol. 2002 May; 22 (10) :3437-49. PubMed PMID:11971975; PubMed Central PMCID: PMC133805.

Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol. 2001 Dec 10; 155 (6) :911-21. PubMed PMID:11739404; PubMed Central PMCID: PMC2150890.

Vazquez J, Belmont AS, Sedat JW. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol. 2001 Aug 21; 11 (16) :1227-39. PubMed PMID:11525737.

Dietzel S, Belmont AS. Reproducible but dynamic positioning of DNA in chromosomes during mitosis. Nat Cell Biol. 2001 Aug; 3 (8) :767-70. PubMed PMID:11483964.

Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21 (13) :4404-12. PubMed PMID:11390668; PubMed Central PMCID: PMC87100.

Belmont AS. Visualizing chromosome dynamics with GFP. Trends Cell Biol. 2001 Jun; 11 (6) :250-7. PubMed PMID:11356361.

Tumbar T, Belmont AS. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. Nat Cell Biol. 2001 Feb; 3 (2) :134-9. PubMed PMID:11175745.

Tsukamoto T, Hashiguchi N, Janicki SM, Tumbar T, Belmont AS, Spector DL. Visualization of gene activity in living cells. Nat Cell Biol. 2000 Dec; 2 (12) :871-8. PubMed PMID:11146650.

Tumbar T, Sudlow G, Belmont AS. Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain. J Cell Biol. 1999 Jun 28; 145 (7) :1341-54. PubMed PMID:10385516; PubMed Central PMCID: PMC2133171.

Belmont AS, Dietzel S, Nye AC, Strukov YG, Tumbar T. Large-scale chromatin structure and function. Curr Opin Cell Biol. 1999 Jun; 11 (3) :307-11. PubMed PMID:10395564.

Belmont AS, Li G, Sudlow G, Robinett C. Visualization of large-scale chromatin structure and dynamics using the lac operator/lac repressor reporter system. Methods Cell Biol. 1999; 58:203-22. PubMed PMID:9891383.

Li G, Sudlow G, Belmont AS. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: precise choreography of condensation/decondensation and nuclear positioning. J Cell Biol. 1998 Mar 9; 140 (5) :975-89. PubMed PMID:9490713; PubMed Central PMCID: PMC2132695.

Belmont AS, Straight AF. In vivo visualization of chromosomes using lac operator-repressor binding. Trends Cell Biol. 1998 Mar; 8 (3) :121-4. PubMed PMID:9695822.

Belmont AS. Nuclear ultrastructure: transmission electron microscopy and image analysis. Methods Cell Biol. 1998; 53:99-124. PubMed PMID:9348506.

Marshall WF, Straight A, Marko JF, Swedlow J, Dernburg A, Belmont A, Murray AW, Agard DA, Sedat JW. Interphase chromosomes undergo constrained diffusional motion in living cells. Curr Biol. 1997 Dec 1; 7 (12) :930-9. PubMed PMID:9382846.

Webb CD, Teleman A, Gordon S, Straight A, Belmont A, Lin DC, Grossman AD, Wright A, Losick R. Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells of B subtilis. Cell. 1997 Mar 7; 88 (5) :667-74. PubMed PMID:9054506.

Minshull J, Straight A, Rudner AD, Dernburg AF, Belmont A, Murray AW. Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr Biol. 1996 Dec 1; 6 (12) :1609-20. PubMed PMID:8994825.

Straight AF, Belmont AS, Robinett CC, Murray AW. GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion. Curr Biol. 1996 Dec 1; 6 (12) :1599-608. PubMed PMID:8994824.

Robinett CC, Straight A, Li G, Willhelm C, Sudlow G, Murray A, Belmont AS. In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J Cell Biol. 1996 Dec; 135 (6 Pt 2) :1685-700. PubMed PMID:8991083; PubMed Central PMCID: PMC2133976.

Pixton JL, Belmont AS. NewVision: a program for interactive navigation and analysis of multiple 3-D data sets using coordinated virtual cameras. J Struct Biol. 1996 Jan-Feb; 116 (1) :77-85. PubMed PMID:8742727.

Delaney AH, Belmont A. Restoration of high-tilt electron micrographs using a focus series. Ultramicroscopy. 1994 Dec; 56 (4) :319-35. PubMed PMID:7831737.

Belmont AS, Bruce K. Visualization of G1 chromosomes: a folded, twisted, supercoiled chromonema model of interphase chromatid structure. J Cell Biol. 1994 Oct; 127 (2) :287-302. PubMed PMID:7929576; PubMed Central PMCID: PMC2120203.

Belmont AS, Zhai Y, Thilenius A. Lamin B distribution and association with peripheral chromatin revealed by optical sectioning and electron microscopy tomography. J Cell Biol. 1993 Dec; 123 (6 Pt 2) :1671-85. PubMed PMID:8276889; PubMed Central PMCID: PMC2290888.